Skunk #1 is a hybrid strain with an Indica dominance. Skunk #1 smells distinctly skunky, and its flavor is a combination of sour and earthy notes. Skunk #1 produces a cerebral high that belies its Indica genetics, as well as full-body relaxation. The head high is energizing and imaginative, while the body high is calming. It can also be used to treat chronic pain, headaches, and appetite loss in addition to anxiety and other mental illnesses.